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Cardiac Markers - Troponin I

Immunoassay ye in vitro quantitative kutsunga kwe cTnI (troponin I Ultra) kusungwa muropa revanhu rose, serum uye plasma.Chiyero che cardiac troponin I chinoshandiswa mukuongororwa uye kurapwa kwemyocardial infarction uye seyamuro munjodzi yekusagadzikana kwevarwere vane acute coronary syndromes maererano nengozi yavo yekufa.


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Troponin ipuroteni inodzora pamhasuru fibers mumasero etsandanyama, ayo anonyanya kudzora kutsvedza kwehama pakati pemafilanti akakora uye akaonda mhasuru panguva yekuputika kwemyocardial.Inoumbwa nezvikamu zvitatu: troponin T (TNT), troponin I (TNI) uye troponin C (TNC).Kutaura kwevatatu subtypes muskeletal muscle uye myocardium inodzorwawo nemajini akasiyana.Izvo zviri mukati me cardiac troponin mu serum yakajairika yakaderera zvakanyanya kupfuura yemamwe ma enzymes emyocardial, asi iyo yekuisa mu cardiomyocytes yakanyanya.Kana iyo myocardial cell membrane isina kusimba, cTnI haigone kupinda musero membrane mukutenderera kweropa.Kana masero emyocardial achipera uye necrosis nekuda kweischemia uye hypoxia, cTnI inosunungurwa muropa kuburikidza nekukuvara kwesero membranes.Iko kusungirirwa kwecTnI kunotanga kusimuka maawa 3-4 mushure mekuitika kweAMI, inokwira pamaawa 12-24, uye inopfuurira kwemazuva 5-10.Nokudaro, kutsunga kwecTnI kuisa muropa kwakava chiratidzo chakanaka chekucherechedza kushanda kwekugadzirisa uye kudzorerazve muvarwere ve AMI.cTnI haina kungova nehutsanana hwakasimba, asiwo ine kunzwisiswa kwakanyanya uye kwenguva refu.Nokudaro, cTnI inogona kushandiswa sechiratidzo chakakosha kubatsira mukuongororwa kwekukuvara kwemyocardial, kunyanya acute myocardial infarction.

Zvikuru Zvikamu

Microparticles (M): 0.13mg/ml Microparticles yakasanganiswa ne anti troponin I ultra antibody
Reagent 1 (R1): 0.1M Tris buffer
Reagent 2 (R2): 0.5μg/ml Alkaline phosphatase yakanyorwa kuti antitroponin I ultra
Kuchenesa mhinduro: 0.05% surfactant, 0.9% Sodium chloride buffer
Substrate: AMPPD mu AMP buffer
Calibrator (kusarudza): Troponin I ultra antigen
Kudzora zvinhu (optional): Troponin I ultra antigen

 

Cherechedza:
1.Zvikamu hazvichinjike pakati pemabheti eagent mitsetse;
2.Ona iyo calibrator bhodhoro label ye calibrator concentration;
3.Ona bhodhoro rekudzora bhodhoro rehuwandu hwehuwandu hwekutonga.

Kuchengetedza Uye Kushanda

1.Kuchengetedza: 2℃~8℃, dzivisa chiedza chezuva.
2.Validity: zvigadzirwa zvisina kuvhurwa zvinoshanda kwemwedzi ye12 pasi pemamiriro akataurwa.
3.Calibrator uye zvinodzora mushure mekunyungudika zvinogona kuchengetwa kwemazuva gumi nemana mu2℃~8℃ yakasviba nharaunda.

Applicable Instrumen

Automated CIA System yeIllumaxbio (lumiflx16, lumiflx16s, lumilite8, lumilite8s).


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