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In vitro diagnostics (IVD) inoita basa rakakosha muindasitiri yehutano, ichigonesa kuongororwa, kurapwa, nekudzivirira zvirwere.Kwemakore, kudiwa kwebvunzo dzeIVD dzinoshanda, dzakarurama, uye dzinodhura zvakakonzera kugadzirwa kweakasiyana matekinoroji ekuongorora.Pakati peaya matekinoroji, chemiluminescence yakabuda sechishandiso chine simba, kushandura ndima yeIVD.

Chemiluminescence: The Basics

Chemiluminescence chiitiko chinoitika kana kemikari ichiita inoburitsa chiedza.MuIVD, kuita kunosanganisira enzyme inokonzeresa kushandurwa kwe substrate kuita chigadzirwa icho, kana oxidation, inoburitsa chiedza.Chemiluminescence-based assays ine huwandu hwakawanda hwekushandisa mukuongororwa, kusanganisira oncology, zvirwere zvinotapukira, uye chirwere chemoyo.

Kukosha kweChemiluminescence muIVD

Kuunzwa kwechemiluminescence muIVD kwakashandura nzira dzekuedzwa dzinoitwa.Kare bvunzo dzekuongorora dzaitora nguva, dzaida masampuli mahombe, uye dzaive dzakadzikama.Chemiluminescence-based assays inopa kunzwisiswa kwepamusoro, hutsananguro, uye hupamhi hune simba renji, zvichiita kuti zvikwanise kuona kunyangwe kudzika kwakadzika kwevaongorori mune diki sampuli vhoriyamu.Migumisiro inowanikwa nokukurumidza uye nekururama kukuru, zvichiita kuti zvive nemigumisiro yakanaka yekliniki.

Nzvimbo-ye-Kutarisira-Kuedza (POCT) 

Mumakore achangopfuura, kwave kuri kuwedzera kudiwa kwePOCT, ongororo yekuongorora yekurapa inoitwa padyo nenzvimbo yekutarisira.POCT yave kuwedzera mukurumbira nekuda kwekureruka kwayo kwekushandisa, kukurumidza mhedzisiro, uye mutengo wakaderera.Chemiluminescence-based POCT assays yave chikamu chese chikamu cheindasitiri yehutano, ichipa vatapi vehutano nemhedzisiro inenge yekukurumidza, kubvisa kudiwa kwekutumira sampuli kurabhoritari kuti iongororwe.

Ramangwana

Musika wechemiluminescence muIVD uchiri kuwedzera, iine fungidziro yekuwedzera yegore negore kukura kwe6% mumakore mashanu anotevera.Kukura uku kuri kukonzerwa nekuwedzera kuri kuita zvirwere zvinotapukira, kukwira kwemari yehutano, uye kudiwa kwekukurumidza kuongororwa bvunzo.Kubuda kwehunyanzvi hutsva hunobatanidza tekinoroji dzakasiyana siyana dzekuongorora, senge chemiluminescence ine microfluidics, inovimbisa maassays anoshanda, kuderedza mitengo uye nguva inodiwa yekuongororwa.

Mhedziso

Chemiluminescence yakashandura munda weIVD uye yave chishandiso chakakosha kune vanopa hutano.Nekurongeka kwayo, kushanda nesimba, uye nekukurumidza mhedzisiro, yakashandura maitirwo anoitwa bvunzo dzekuongorora.Kushandiswa kwaro muPOCT kwakagonesa varwere vazhinji kuti vagamuchire kuongororwa nenguva uye kurapwa, vachiponesa hupenyu.Nekufambira mberi mune tekinoroji uye nyowani assays, ramangwana rechemiluminescence muIVD rinotaridzika kupenya.


Nguva yekutumira: May-17-2023