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Nepo kwenguva refu COVID inobata zvakavanzika zvakawanda, vaongorori vakawana zvinongedzo kune zvakajairwa zviratidzo zvemoyo muvarwere ava, zvichiratidza kuti kuzvimba kunoramba kuripo muyananisi.
Muboka revanhu mazana matatu nemakumi mana nevatanhatu vaimbove vane hutano hweCCIDID-19, vazhinji vacho vakaramba vaine zviratidzo mushure memwedzi ingangoita 4, kukwidzwa kwema biomarkers echirwere chemoyo uye kukuvara kwemoyo kana kusashanda zvakanaka kwaisawanzoitika.
Asi pane zviratidzo zvakawanda zve subclinical heart problems, shuma Valentina O. Puntmann, MD, University Hospital Frankfurt, Germany, uye vaanoshanda navo paNature Medicine.
Kuenzaniswa neasina kutapukirwa kudzora, varwere veCOVID vaive nepamusoro diastolic yeropa, zvakanyanya kuwedzera kusiri-ischemic myocardial mavanga nekuda kwekunonoka kukwidziridzwa kwegadolinium, inooneka isina-hemodynamically yakabatana pericardial effusion, uye pericardial effusion.<0,001). <0.001).
Uye zvakare, makumi manomwe neshanu muzana evarwere veCCIDID-19 vane zviratidzo zvemoyo vaive nepamusoro pemoyo MRI (CMR) yemepu kukosha pane asymptomatic vanhu, zvichiratidza kupararira kwemyocardial kuzvimba uye kuunganidza kukuru kwekusiyana kwepericardial.
"Zvatiri kuona hazvina kunaka," Puntmann akaudza MedPage Nhasi."Ava vanga vari varwere vakajairwa kare."
Mukupesana neicho chinowanzo fungwa kuti idambudziko remoyo neCCIDID-19, mhedzisiro idzi dzinopa ruzivo rwekuti varwere vane matambudziko emoyo agara aripo vanogona kupihwa muchipatara nehurwere hwakakomba nemhedzisiro.
Boka raPuntman rakadzidza vanhu vasina matambudziko emoyo kuyedza kunzwisisa maitiro eCCIDID-19 pachayo, vachishandisa tsvakiridzo-giredhi MRI mifananidzo yevarwere vanotorwa kumakiriniki avo kuburikidza navanachiremba vemhuri, zvipatara zvehutano, zvinhu zvekusimudzira zvakagoverwa nevarwere pamhepo.Mapoka nemawebhusaiti..
Puntmann akacherekedza kuti kunyangwe iri riri boka rakasarudzwa revarwere vangango miririra zvinyoro zveCCIDID-19, hazvina kujairika kuti varwere ava vatsvage mhinduro kuzviratidzo zvavo.
Federal ongororo data inoratidza kuti 19 muzana yevakuru vekuAmerica vakatapukirwa neCOVID vaive nezviratidzo zvemwedzi mitatu kana kupfuura mushure mekutapukirwa.Muchidzidzo chazvino, kuteedzera kunotarisa avhareji yemwedzi gumi neimwe mushure mekuongororwa kweCCIDID-19 kwakaratidza zvinoramba zvichiratidza zviratidzo zvemoyo mu57% yevatori vechikamu.Avo vakaramba vaine zviratidzo vaiva nemyocardial edema yakawanda kupfuura avo vakapora kana kuti vasina kumbova nezviratidzo (zvakasikwa T2 37.9 vs 37.4 uye 37.5 ms, P = 0.04).
"Kubatanidzwa kwemoyo chikamu chakakosha chekuratidzwa kwenguva refu kweCOVID - saka dyspnea, kusashivirira, tachycardia," Pontman akadaro mubvunzurudzo.
Boka rake rakagumisa kuti zviratidzo zvemwoyo zvavakaona "zvakabatana nechirwere chemoyo chinozvimba, chinogona kutsanangura, pamwe muchikamu, hwaro hwepathophysiological hwekuramba kwezviratidzo zvemoyo.Sezvineiwo, kukuvara kwakanyanya kwemyocardial kana chirwere chemoyo chechimiro hachisi chimiro chisati chavapo uye zviratidzo zvacho hazvienderane netsanangudzo yechinyakare yehutachiona myocarditis. "
Cardiologist uye murwere wenguva refu weCOVID Alice A. Perlowski, MD, akataura zvakakosha zvekiriniki nekuita tweeting achiti: "Chidzidzo ichi chinotaridza kuti chinyakare biomarkers (munyaya iyi CRP, tsandanyama calcin, NT-proBNP) inogona kusataura nyaya yese. ”., #LongCovid, ndinovimba kuti vese varapi vanoona varwere ava vachidzidzira vanogadzirisa pfungwa iyi yakaoma. "
Pakati pevakuru mazana matatu nemakumi mana nevatanhatu vane COVID-19 (ane makore 43.3, vakadzi makumi mashanu neshanu muzana) vakaongororwa panzvimbo imwe pakati paKubvumbi 2020 naGumiguru 2021, panguva yepakati pemazuva zana mushure mekufumurwa, chiratidzo chemoyo chakanyanya kupfupika kwekufema (62% ), palpitations (28%), atypical chest pain (27%), uye syncope (3%).
"Kuziva zviri kuitika nekuongororwa kwemoyo nguva dzose idambudziko nekuti zvakaoma kuona mamiriro asina kunaka," akadaro Puntmann.“Chimwe chazvo chine chekuita nezvirwere zviri seri kwayo… Kunyange kana basa ravo rikakanganiswa, hazvishamisi nekuti vanotsiva tachycardia uye nemoyo unofara.Naizvozvo, hatina kuvaona muchikamu chakabviswa. ”
Chikwata ichi chinoronga kuenderera mberi nekutevera varwere ava kwenguva yakareba kuti vanzwisise zvingangoitika mukiriniki, vachityira kuti "zvinogona kuzivisa mutoro mukuru wekutadza kwemoyo makore munzira," sekureva kwewebsite yenzvimbo.Dare racho rakatangawo MYOFLAME-19 placebo-controlled controlled study kuti iedze anti-inflammatory drugs nemishonga inoshanda pane renin-angiotensin system muhuwandu huno.
Chidzidzo chavo chaisanganisira varwere chete vasina kumbobvira vazivikanwa chirwere chemoyo, comorbidities, kana abnormal mapapu basa bvunzo pakutanga uye vanga vasati vambopinda muchipatara cheacute COVID-19.
Vamwe varwere makumi mapfumbamwe nevashanu pakiriniki vanga vasina yekutanga COVID-95 uye vasina chirwere chemoyo chinozivikanwa kana comorbidities vakashandiswa sekutonga.Nepo vaongorori vakabvuma kuti panogona kunge paine misiyano isingazivikanwe kana ichienzaniswa nevarwere veCOVID, vakacherekedza kugovera kwakafanana kwezvinhu zvine njodzi nezera, murume kana mukadzi, uye chirwere chemoyo.
Pakati pevarwere vane zviratidzo zveCCIDID, ruzhinji rwaive rwakapfava kana pakati nepakati (38% uye 33%, zvichiteerana), uye vapfumbamwe chete (3%) vaive nezviratidzo zvakakomba zvaiganhurira zviitiko zvezuva nezuva.
Zvinhu zvakazvimiririra kufanotaura zviratidzo zvemoyo kubva pakutanga scan kuti idzokorore ingangoita mwedzi 4 gare gare (yepakati 329 mazuva mushure mekuongororwa) yaive yechikadzi uye yakapararira kubatanidzwa kwemyocardial pane yekutanga.
"Zvakaoma, nekuti kudzidza kwedu kwakanangana nevanhu vane pre-COVID chirwere, hakuna kuudza kuwanda kweiyo post-COVID moyo zviratidzo," boka raPuntman rakanyora."Zvisinei, inopa ruzivo rwakakosha nezve spectrum yavo uye kushanduka kunotevera."
Puntmann nemumwe munyori vakaburitsa mari dzekutaura kubva kuBayer neSiemens, pamwe nemari yedzidzo kubva kuBayer neNeoSoft.
Kwakabva citation: Puntmann VO et al "Nguva refu yemwoyo pathology muvanhu vane hunyoro hwekutanga COVID-19 chirwere", Nature Med 2022;DOI: 10.1038/s41591-022-02000-0.
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